Abstract The Sandals development of granulomas with central necrosis harboring Mycobacterium tuberculosis (Mtb) is the hallmark of human tuberculosis (TB).New anti-TB therapies need to effectively penetrate the cellular and necrotic compartments of these lesions and reach sufficient concentrations to eliminate Mtb.BTZ-043 is a novel antibiotic show

Soft skills and employee productivity are key factors in sustainability and corporate performance in competitive and dynamic environments.The purpose of this article is to identify current findings related to soft skills, employee productivity and their relationship with organizational performance, and to propose a structural model that allows esta

Extrachromosomal circular DNA (eccDNA) facilitates adaptive evolution by allowing rapid and extensive gene copy number variation and is implicated in the pathology of cancer and ageing.Here, we demonstrate that yeast aged under environmental copper accumulate high levels of eccDNA containing the copper-resistance gene Face Wash CUP1.Transcription o

Introduction Functional constipation (FC) is a common digestive system disease, with an uptrend in morbidity and mortality, resulting in huge social and economic losses.Although the guidelines recommend lifestyle intervention as a first-line treatment, lifestyle intervention is not widely used in clinic.Inulin can be used as the basic material of f